The Francis Crick Stem Cell Forum

The Crick stem cell forum is a diverse network of researchers who share a passion for stem cell and developmental biology.

Our goal is to foster collaboration and interaction between labs across London and beyond by highlighting the exciting work being carried out in the field of stem cell research.

Anyone with an interest in this area is encouraged to present or attend. 
Meeting on the first Tuesday of each month, the forum is a welcoming and open space, providing a fantastic opportunity for researchers to present their work and in turn receive invaluable feedback from their peers.

Currently, we have representation from numerous research institutes and cover a broad range of areas beyond just the basic stem cell biology, including embryology and development, cancer and novel therapeutic applications.

We are always looking for more researchers who share our interests to join the forum and benefit from being part of the brilliant community of scientists it has created.
We look forward to meeting you soon!

The Crick Stem Cell Forum Committee

Email: scf@crick.ac.uk


Stem Cell Forum Webinars

Upcoming Forums
6thJuly 2021, 3.30pm
Leanne Bradley, Edinburgh/Queen’s University Belfast "Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion"

7thSept 2021, 3.30pm

Prof Jason Spence, University of Michigan Medical School “Mapping Development of the Human Intestinal Niche at Single-Cell Resolution”

Dr Kathleen Shah, The Francis Crick Institute "AHR in tissue regeneration: a missing link between diet, environment and colorectal cancer development?"

Previous Forums

12th January 2021, 3.30pm Dr Ana Maria Ranzoni "Lineage tracing of human embryonic development and foetal haematopoiesis through somatic mutations" & Rebecca Lea "Identifying novel regulators of human pluripotency"

16th February 2021, 3.30pm Prof. Isabel Fariñas "Adult Neural Stem Cells Are Alerted by Systemic Inflammation through TNF-α Receptor Signaling" & Dr Luca Tosti "Single nucleus and in situ RNA sequencing reveals cell topographies in the human pancreas"

16th March 2021, 3.30pm Dr. Kevin Rouault-Pierre “Causes and consequences of metabolic deficiency induced by mutations in splicing factors” & Dr. Alison McGarvey “Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in wildtype and cloche/npas4lmutant zebrafish embryos”

13th April 2021, 3.30pm Dr Teresa Rayon Alonso “Molecular profiling of the developing neural tube and peripheral nervous system from human embryos” & Jorge Almargo “Wnt drives chemoresistance of mammary cancer stem cells”

18th May 2021, 3.30pm

 

Dr. Roshana Thambyrajah (Anna Bigas Lab) – (IMIM-PRBB, Barcelona)

“Exploring alternative inflammatory signals in HSC development”

Rebekka Schneider-Kramann, MD, PhDProfessor of Cell Biology
Institute for Biomedical Engineering University Hospital RWTH Aachen, Netherlands

1stJune 2021, 3.30pm

Dr. Owen Tamplin, University of Wisconsin-Madison: “Novel approaches to resolve the hematopoietic stem cell niche”

Dr. Otto Morris, Santos Lab Francis Crick Institute: “Warburg-like Metabolic Reprogramming in Aging Intestinal Stem Cells Contributes to Tissue Hyperplasia"

Webinar login information

Details for joining the online webinar:

Please click this URL to join. https://crick.zoom.us/s/64275324274?pwd=dlFnREJMQmlVMG9Lcm9EM0VjRWhNUT09
Password: 627065

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Dial(for higher quality, dial a number based on your current location):
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Previous Stem Cell Forums (Click date for full details)

2020

25th March

12th May, 3pm. Dr Miguel Ganuza ” Clonal dynamics of embryonic and early-post-birth blood precursors” & Dr Bruno Federico “ The serendipitous journey of DNGR-1 lineage tracing in the central nervous system”

26th May, 3pm. Dr Paolo Gallipoli “The role of metabolic adaptations in the resistance to targeted therapy in Acute Myeloid Leukaemia” & Dr Matthew Witkowski “The Evolving Immune Landscape of B cell Acute Lymphoblastic Leukaemia"

9th June, 3.30pm. Dr Davide Danovi “Imaging cells: defining objects, capturing identities, testing boundaries” & Dr Talya Dayton “Organoid models of neuroendocrine cell growth and tumorigenesis”

23rd June, 3.30pm. Dr Francesco Saverio Tedesco "Human iPS cells and bioengineered muscles for disease modelling and therapy development" & Dr Constandina Pospori “Dynamic regulation of hierarchical heterogeneity in Acute Myeloid Leukaemia serves as a tumour immunoevasion mechanism”

7th July, 3.30pm. Dr Rita Sousa-Nunes "A new evolutionarily conserved mechanism of regulating (neural) stem cell quiescence" & Prof Sian Harding "Human pluripotent stem cell derivatives in engineered heart tissue"

21st July, 3.30pm. Dr Elspeth Payne, “Dissecting the role of Cebpa leukamogenic alleles in developmental haematopoiesis” Dr. Joaquina Delas Vives “Building a molecular mechanistic model for developmental cis-regulatory elements” & Dr. Mathias Holpert "An introduction and overview of GeoMx Digital Spatial Profiler, and how this technology delivers Digital Counts of Biomarker expression levels in precise SPATIAL context, enabling researchers to deepen the understanding of heterogeneity and disease, and accelerate the development of next generation targeted therapeutics!"

4th August, 3.30pm. Prof. Cristina Lo Celso “Healthy and malignant haematopoiesis: dynamic cells in an evolving environment” & Dr Claudia Gerri “A conserved molecular cascade initiates a trophectoderm program in human, cow and mouse embryos prior to blastocyst formation”

1st September, 3.30pm. Dr. Periklis Pantazis "GenEPI-Piezo1-based fluorescent reporter for visualising mechanical stimuli with high spatiotemporal resolution" & Dr. Amanda Andersson Rolf"Transcriptional changes during pancreatic endocrine differentiation in real time at single-cell level"

29th September, 3.30pm Dr. António Salgado "Mesenchymal Stem Cells Secretome as a Modulator of CNS Regeneration" & Dr. Christa Haase “AML-stromal crosstalk by in vivo imaging and spatially-resolved single-cell transcriptomics”

27th October, 3.30pm Dr Ana Cardoso "Unexpected role of IL-10 as a trigger of emergency myelopoiesis"  & Dr Paola Bonfanti"Reconstitution of a functional human thymus by progenitor cells and natural whole-organ scaffolds"

24th November, 3.30pm Dr Kerstin Kaufmann "A distinct subset of human haematopoietic stem cells resist regenerative stress to preserve stemness" & Dr Nicole Mende “Distinct cellular reservoirs of human haematopoietic stem and progenitor cells outside the bone marrow.”

15th December, 3.30pm Dr Rhys Morgan "Targeting the β-catenin protein interaction network in myeloid cells" & Dr Edie Crosse "Multi-layered spatial transcriptomics identify secretory factors promoting human hematopoietic stem cell development"

2019
2018
2017

Stem Cell Forum Videos

Our full library of videos can be found at the LSCN YouTube Channel.

Dr Matthew Witkowski “The Evolving Immune Landscape of B cell Acute Lymphoblastic Leukaemia
Dr Davide Danovi “Imaging cells: defining objects, capturing identities, testing boundaries”
Dr Talya Dayton “Organoid models of neuroendocrine cell growth and tumorigenesis”
Dr Elspeth Payne “Dissecting the role of Cebpa leukamogenic alleles in developmental haematopoiesis”
Dr. Periklis Pantazis “GenEPI-Piezo1-based fluorescent reporter for visualising mechanical stimuli with high spatiotemporal resolution”
Prof Cristina Lo Celso “Healthy & malignant haematopoiesis: dynamic cells in an evolving environment”

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