1st London Stem Cell Network Symposium – 2018
Programme
8:30 – Registration
9:00 – Opening remarks: Launching the London Stem Cell Network – William Grey (The Francis Crick Institute)
Tissue/Adult stem cells
Chairs: Dominique Bonnet (The Francis Crick Institute) and Ines Sequeira (King’s College London)
9:05 – Key note speaker: Fiona Watt (King’s College London) – “Homeostasis in Adult Mammalian Epidermis”
9:40 – Short talk: Jamie McGinn (University of Cambridge) – “Postnatal Cell Dynamics; Finding the path towards Oesophageal Homeostasis”
9:55 – Short talk: Joana Carrelha (University of Oxford) – “Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells”
10:10 – Simona Parrinello (University College London) – “Microenvironmental control of somatic cell plasticity in tissue regeneration”
10:35 – Coffee break
Cancer Stem Cells
Chairs: Cristina Lo Celso (Imperial College London) and Virginia Turati (University College London)
10:50 – Beth Payne (University College London) – “In vivo small molecule screens identify TLR7 agonists as potential therapeutics targeting HSPC in MDS5q”
11:15 – Short talk: Manav Pathania (University College London) – “H3.3-K27M Expression and Trp53 Loss in Embryonic Neural Stem Cells Induces Gliomagenesis”
11:30 – Short talk: Kevin Rouault-Pierre (Barts Cancer Institute) – “Integrative profiling, xenograft and genomics reveal JMML’s origin”
11:45 – Short talk: Simon Richardson (University College London) – “A human IPS model implicates embryonic B-myeloid fate restriction as a developmental susceptibility to ETV6-RUNX1”
12:00– Trevor Graham (Queen Mary, University of London) – “Tracing stem cell architecture in vivo in human tissues and cancer”
12:25 – Lunch + Posters
Bioengineering the stem cell environment
Chairs: Davide Danovi (King’s College London) and Diana Passaro (The Francis Crick Institute)
13:45 – Vivian Li (The Francis Crick Institute) – “Stem cell-derived organoids: disease modelling and regenerative medicine”
14:10 – Short talk: Alessandro Filippo Pellegata (University College London) – “Vascularisation for whole organ tissue engineering”
14:25 – Short talk: Elisa Pedone (University of Bristol) – “In-Silico control of Wnt/β-catenin pathway in mammalian cells using microfluidics”
14:50 – Eileen Gentleman (King’s College London) – “Unravelling how bi-directional cell-biomaterial interactions direct stem cell fate in 3D”
Regenerative medicine
Chairs: Molly Stevens (Imperial College London) and Luca Pinton (University College London)
15:15 – Kathy Niakan (The Francis Crick Institute) – “Mechanisms of lineage specification in human embryos”
15:40 – Short talk: Shirin Issa Bhaloo (King’s College London) – “Dickkopf-3 binds to CXCR7 inducing vascular progenitor cell migration and degradable graft cellularisation”
15:55 – Short talk: Eleonora Zucchelli (University College London) – “Potential of patient-derived ear and fat stem cells for the reconstruction of congenitally malformed ear cartilage”
16:10 – Samuel Janes (University College London) – “Cell and Gene Therapy for Lung Cancer”
16:35 – Coffee break
Chair: Sian Harding (Imperial College London)
16:55 – Key note speaker: Costanza Emanueli (Imperial College and University of Bristol) – “Therapeutic Angiogenesis in Ischemic Disease: Cellular and Acellular Options”
17:35 – Awards
17:40 – Closing remarks – Ines Sequeira (King’s College London)
17:50 – Posters, Drinks and Networking